Sodium Acetate → 3-Acetoxypropyltrivinylsilane

HRID 217567

반응식

HRID 217567 반응식
Cl[CH2:2][CH2:3][CH2:4][Si:5]([CH:10]=[CH2:11])([CH:8]=[CH2:9])[CH:6]=[CH2:7].[C:12]([O-:15])(=[O:14])[CH3:13].[Na+]>CN(C)C=O>[C:12]([O:15][CH2:2][CH2:3][CH2:4][Si:5]([CH:10]=[CH2:11])([CH:8]=[CH2:9])[CH:6]=[CH2:7])(=[O:14])[CH3:13]

참가 물질

4

반응물 2

HCID 517045Sodium AcetateHCID 23630656Trivinyl(3-chloropropyl)silane

생성물 1

HCID 579455963-Acetoxypropyltrivinylsilane수율 76%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
120 °C

실험 절차

As shown in Reaction Scheme 24, 3-chloropropyltrivinylsilane (1.0 g, 5.35 mmol) and sodium acetate (0.87 g, 10.7 mmol) were dissolved in 17 mL of dimethylformamide (DMF), and the reaction mixture was heated at 120° C. for 12 hours. After the reaction, the organic layer was separated after addition of distilled water and ether. The organic layer was dried over MgSO4, concentrated by evaporation of solvent, and the resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4) to give 855 mg (76% yield) of pure 3-acetoxypropyltrivinylsilane.

후처리

  1. customAfter the reaction
  2. customthe organic layer was separated
  3. additionafter addition of distilled water and ether
  4. dry with materialThe organic layer was dried over MgSO4
  5. concentrationconcentrated by evaporation of solvent
  6. customthe resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4)

출처 및 근거

ORD 기록
ord-672dfd5c3911452085a6ee1da2c6cf62
출처 데이터셋
uspto-grants-2012_06
특허 번호
US08197903B2

연결된 노트

불러오는 중…