Dichloromethane → 3-Chloro-1-(3-thienyl)-1-propanone
반응식
[S:1]1[CH:5]=[CH:4][C:3]([C:6](=[O:9])[CH:7]=[CH2:8])=[CH:2]1.[Cl:10]CCl>C(OCC)C.Cl>[Cl:10][CH2:8][CH2:7][C:6]([C:3]1[CH:4]=[CH:5][S:1][CH:2]=1)=[O:9]참가 물질
5
실험 절차
The product from step (b) (1.288 g, 9.3 mmol) was dissolved in a mixture of diethyl ether (30 ml) and dichloromethane (20 ml) and 1M hydrochloric acid in diethyl ether (25 ml) added. The reaction was stirred for 18 h at room temperature. The solvent was removed in vacuo to give the title compound (1.482 g, 91%).
후처리
- additionadded
- customThe solvent was removed in vacuo
출처 및 근거
- ORD 기록
- ord-5a3f24bade6d41e8a5539e8cdf4d5aaa
- 출처 데이터셋
- uspto-grants-2005_05
- 특허 번호
- US06887871B2
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