Acetic Anhydride → 2-Acetoxy-3-methoxybenzaldehyde
반응식
[C:1](OC(=O)C)(=[O:3])[CH3:2].[CH3:8][O:9][C:10]1[CH:17]=[CH:16][CH:15]=[C:12]([CH:13]=[O:14])[C:11]=1[OH:18].C([O-])([O-])=O.[K+].[K+]>C(Cl)Cl>[C:1]([O:18][C:11]1[C:10]([O:9][CH3:8])=[CH:17][CH:16]=[CH:15][C:12]=1[CH:13]=[O:14])(=[O:3])[CH3:2]참가 물질
5
실험 절차
Acetic anhydride (45.9 g, 0.45 mol) was added to a suspension of 3-methoxysalicylaldehyde (45.6 g, 0.3 mol) and K2CO3 (42.0 g, 0.6 mol) in CH2Cl2 (450 L) at rt. The reaction mixture was stirred at rt overnight then filtered, evaporated and the residue was recrystallised from cyclohexane to give 42 (42.0 g, 74%) as colourless needles:
후처리
- filtrationthen filtered
- customevaporated
- customthe residue was recrystallised from cyclohexane
출처 및 근거
- ORD 기록
- ord-e4efdb52c67c4a0e99b2eef199743808
- 출처 데이터셋
- uspto-grants-2012_06
- 특허 번호
- US08198302B2
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