Sodium Bicarbonate → 2,7-Dibromocarbazole
반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][C:9]=2N)=[C:4]([NH2:16])[CH:3]=1.C([O-])(O)=O.[Na+]>P(=O)(O)(O)O>[Br:14][C:11]1[CH:12]=[CH:13][C:8]2[C:5]3[C:4](=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=3)[NH:16][C:9]=2[CH:10]=1참가 물질
4
반응 조건
- 온도
- 190 °C
실험 절차
4,4′-dibromo-2,2′-diaminobiphenyl (3.5 g, 10.23 mmol) was dissolved in phosphoric acid and heated at 190° C. for 24 hours. The reaction mixture was cooled to room temperature and then NaHCO3 (aq) was gradually added thereto to form a solid. Then, the solid was filtered to obtain 2,7-dibromocarbazole (2.2 g, 66%), the compound represented by formula e. MS [M+] 323.
후처리
- temperatureThe reaction mixture was cooled to room temperature
- customto form a solid
- filtrationThen, the solid was filtered
출처 및 근거
- ORD 기록
- ord-ebd10a7ee021428fa542efc353b75e72
- 출처 데이터셋
- uspto-grants-2012_06
- 특허 번호
- US08198801B2
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