Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Glycinate → [(4-Hydroxy-2-oxo-7-phenoxy-2H-chromene-3-carbonyl)-amino]-acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Glycinate | HCID 4684308 | — |
| 반응물 | 4-Hydroxy-2-oxo-7-phenoxy-2H-chromene-3-carboxylic acid ethyl ester | HCID 86649463 | — |
| 용매 | 1-Methoxyethanol | HCID 3015637 | — |
| 생성물 | [(4-Hydroxy-2-oxo-7-phenoxy-2H-chromene-3-carbonyl)-amino]-acetic acid | HCID 54746545 | 105.5% |
반응 단계
A mixture of 4-hydroxy-2-oxo-7-phenoxy-2H-chromene-3-carboxylic acid ethyl ester (84 mg, 0.248 mmol) and sodium glycinate (121 mg, 1.24 mmol) in methoxyethanol (5 mL) was refluxed for 15 h; then cooled, the solvent was removed, the residue was redissolved in water, acidified with 2 M HCl, the precipitates were collected and freeze dried to give the desired title product (93 mg). ESI (m/z): 356 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08324405B2 |
| 출처 데이터셋 | uspto-grants-2012_12 |
| ORD ID | ord-a0e542033fb84b4fa4e6abcd8255e9c0 |
| 출처 메모 | uspto-grants-2012_12 |