참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | Sulfolane | HCID 31347 | — |
| 반응물 | 5-Acetamido-1-(acetyloxy)naphthalene-2-sulfonic acid | HCID 155698 | — |
| 생성물 | 2-Naphthalenesulfonyl chloride, 5-(acetylamino)-1-(acetyloxy)- | HCID 94125 | 81% |
반응 단계
100 g of 1-acetoxy-5-acetaminonaphthalene-2-sulfonic acid was added to 500 ml of sulfolane, and 200 ml of phosphorus oxychloride was dropwise added thereto at 40° C. while stirring. After continuing stirring for about 1 hour, the reaction mixture was poured into 2 liters of ice-water, and the precipitated crystals were collected by filtration, washed with water until the filtrate did not show acidity, and air-dried as such for 24 hours to obtain 70 g (81% yield) of product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04358532 |
|---|
| 출처 데이터셋 | uspto-grants-1982_11 |
|---|
| ORD ID | ord-b241a5edfd5e451ebbba5e3298b4e286 |
|---|
| 출처 메모 | uspto-grants-1982_11 |
|---|
