4-Hydroxybenzyl Alcohol → Phenol, 4-[(ethylthio)methyl]-
반응식
O[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.[CH2:10]([SH:12])[CH3:11].C1(O)C=CC=CC=1>>[CH2:10]([S:12][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1)[CH3:11]참가 물질
4
반응 조건
- 온도
- 85 °C
실험 절차
A mixture of 62 g (0.5 mol) of 4-hydroxymethyl-phenol, 37 g (0.6 mol) of ethylmercaptan and 230 g of phenol was first heated, in a flask equipped with stirrer and reflux condenser, under normal pressure to about 85° C. in the course of about 15 minutes, and was then heated further in such a way that there was always a moderate reflux and that ultimately a final temperature of about 130° C. in the flask was reached. After a reaction time of 18 hours at 85°-130° C., the mixture was cooled and worked up by distillation. 4-Ethylthiomethyl-phenol was obtained in a yield of 65% of theory.
후처리
- temperaturewas first heated, in a flask
- customequipped with stirrer
- temperaturereflux condenser
- temperaturea moderate reflux
- customtemperature of about 130° C.
- temperatureAfter a reaction time of 18 hours at 85°-130° C., the mixture was cooled
- distillationworked up by distillation
출처 및 근거
- ORD 기록
- ord-9fd21d3d36b04fc0b927571eaf3ad146
- 출처 데이터셋
- uspto-grants-1982_11
- 특허 번호
- US04358616
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