Benzotrichloride → Propanoyl chloride, 3-bromo-2,2,3,3-tetrafluoro-

반응식

[Br:1][C:2]([F:10])([F:9])[C:3]([F:8])([F:7])[C:4](O)=[O:5].C1(C(Cl)(Cl)[Cl:18])C=CC=CC=1>>[Br:1][C:2]([F:10])([F:9])[C:3]([F:8])([F:7])[C:4]([Cl:18])=[O:5]

참가 물질

반응물 2

HCID 7367Benzotrichloride

HCID 133289113-Bromo-2,2,3,3-tetrafluoropropanoic acid

생성물 1

HCID 10490449Propanoyl chloride, 3-bromo-2,2,3,3-tetrafluoro-수율 71%

실험 절차

A mixture of 375.9 g (1.67 mol) of 3-bromotetrafluoropropionic acid, 10 g of ferric chloride, and 488.7 g (2.50 mol) of benzotrichloride was refluxed for 1.5 h, then crude product was removed, bp about 60°. Redistillation gave 287.9 g (71%) of 3-bromotetrafluoropropionyl chloride, bp 67°-68°. IR (CCl4): 5.53 (C=O). ##STR43##

후처리

temperaturewas refluxed for 1.5 h
customcrude product was removed
distillationRedistillation

출처 및 근거

ORD 기록: ord-55ce83c957424924b2eb37fe082ca3bf
출처 데이터셋: uspto-grants-1982_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04360645

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