Hydrazine hydrate (1:1) → 4-Methoxy-N-[2-nitro-4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]benzamide
반응식
O.[NH2:2][NH2:3].C[O:5][C:6](=O)[CH2:7][CH:8]([C:10](=O)[C:11]1[CH:16]=[CH:15][C:14]([NH:17][C:18](=[O:27])[C:19]2[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=2)=[C:13]([N+:28]([O-:30])=[O:29])[CH:12]=1)[CH3:9]>C(O)(=O)C>[CH3:9][CH:8]1[C:10]([C:11]2[CH:16]=[CH:15][C:14]([NH:17][C:18](=[O:27])[C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=3)=[C:13]([N+:28]([O-:30])=[O:29])[CH:12]=2)=[N:3][NH:2][C:6](=[O:5])[CH2:7]1참가 물질
4
실험 절차
20 ml of 80% hydrazine hydrate were added dropwise to 150 ml of glacial acetic acid while stirring and ice cooling. After cooling, 10.7 gm of 3-[3-nitro-4-(4-methoxybenzoylamino)-benzoyl]-butyric acid methyl ester were added and the mixture was refluxed for 40 minutes. After cooling, 250 ml of ice water were added, and the precipitate formed was suction filtered and washed with ice water.