Chloroacetone → HCID 90402786, 화합물

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[C:1]([CH2:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([NH2:9])=[O:8])#[N:2].Cl[CH2:14][C:15](=O)[CH3:16]>>[CH3:16][C:15]1[N:9]=[C:7]([C:6]2[CH:5]=[C:4]([CH2:3][C:1]#[N:2])[CH:12]=[CH:11][CH:10]=2)[O:8][CH:14]=1

참가 물질

반응물 2

HCID 6571Chloroacetone

HCID 211051423-(Cyanomethyl)benzamide

생성물 1

HCID 90402786HCID 90402786, 화합물

실험 절차

A solution of 3-(cyanomethyl)benzamide (200 mg, 1.25 mmol) in 1-chloropropan-2-one (2 mL) was microwave irradiated at 120 for 20 min in a sealed tube. The mixture was concentrated to give crude product (110 mg), which was directly used to the next reaction without purification. LCMS MH+ 199.

후처리

concentrationThe mixture was concentrated

출처 및 근거

ORD 기록: ord-a67079d97cd44a5fa76841c3a5d6db89
출처 데이터셋: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09359359B2

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