Hydrochloric Acid → (R)-2-amino-2-cyclopropylacetamide hydrochloride
반응식
[NH2:1][C:2](=[O:15])[C@H:3]([NH:7]C(=O)OC(C)(C)C)[CH:4]1[CH2:6][CH2:5]1.[ClH:16]>O1CCOCC1>[ClH:16].[NH2:7][C@H:3]([CH:4]1[CH2:6][CH2:5]1)[C:2]([NH2:1])=[O:15]참가 물질
4
실험 절차
A solution of (R)-tert-butyl 2-amino-1-cyclopropyl-2-oxoethylcarbamate (300 mg, 1.40 mmol) in 4N HCl in dioxane (8 mL) was stirred at room temperature for 20 min. It was then concentrated in vacuo to give (R)-2-amino-2-cyclopropylacetamide hydrochloride (225 mg).
후처리
- concentrationIt was then concentrated in vacuo
출처 및 근거
- ORD 기록
- ord-d47152a3947f4140940e6fe980514e92
- 출처 데이터셋
- uspto-grants-2016_06
- 특허 번호
- US09359375B2
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