Hydrazine hydrate (1:1) → HCID 4164367, 화합물
반응식
CS[C:3]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[C:4]([C:7]#[N:8])[C:5]#[N:6].O.[NH2:17][NH2:18]>CCO>[NH2:6][C:5]1[NH:18][N:17]=[C:3]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:4]=1[C:7]#[N:8]참가 물질
4
실험 절차
Dissolved 2-((methylthio)(phenylamino)methylene)malononitrile (3.2 g) in EtOH (100 mL) and added hydrazine hydrate (1 eq), then heated to reflux until complete by TLC (absence of starting material, 18 hrs). Poured into ice water and filtered to obtain 5-amino-3-(phenylamino)-1H-pyrazole-4-carbonitrile as a yellow powder.
후처리
- temperatureheated
- temperatureto reflux until complete by TLC (absence of starting material, 18 hrs)
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-8e924ff2dc0d49d6875015eca47a8806
- 출처 데이터셋
- uspto-grants-2016_06
- 특허 번호
- US09365556B2
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