Hydrogen chloride-ethyl acetate → Oxan-4-ylhydrazine dihydrochloride

HRID 2205996

반응식

HRID 2205996 반응식
[O:1]1[CH2:6][CH2:5][CH:4]([NH:7][NH:8]C(OC(C)(C)C)=O)[CH2:3][CH2:2]1.C(OCC)(=O)C.[ClH:22]>>[ClH:22].[ClH:22].[O:1]1[CH2:6][CH2:5][CH:4]([NH:7][NH2:8])[CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 45092245N'-(oxan-4-yl)(tert-butoxy)carbohydrazide

생성물 1

HCID 50988431Oxan-4-ylhydrazine dihydrochloride

실험 절차

tert-Butyl 2-(tetrahydro-2H-pyran-4-yl)hydrazinecarboxylate (1.82 g) was dissolved in 4N hydrogen chloride-ethyl acetate solution (85 mL) under ice-cooling, and the solution was stirred overnight at room temperature. The reaction mixture was concentrated under reduced pressure to give the title compound (1.52 g).

후처리

  1. temperaturecooling
  2. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-e0bf9401af274c7fb0f43c5a4cd2ab76
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09371320B2

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