Hydrogen Peroxide → Catechol

HRID 22104

반응식

HRID 22104 반응식
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:8]1[CH2:13][CH2:12][O:11]CC1.OO>C1COC(N2C(=O)NC(=O)C(F)=C2)C1.O>[C:1]1([CH:6]=[CH:5][C:4]([OH:8])=[CH:3][CH:2]=1)[OH:7].[C:13]1([C:12](=[CH:6][CH:1]=[CH:2][CH:3]=1)[OH:11])[OH:8]

참가 물질

7

반응물 3

HCID 784Hydrogen PeroxideHCID 996PhenolHCID 312751,4-Dioxane

생성물 2

HCID 289CatecholHCID 785Hydroquinone

시약·촉매·용매 2

HCID 5386Tegafur촉매HCID 962Water용매

반응 조건

온도
70 °C

실험 절차

A stirrer, a cooler and a temperature indicator were provided to a four-necked flask having an internal volume of 200 ml; to this flask, 13.0 g of phenol, 4.0 g of 1,4-dioxane, 6.0 g of water and 1.3 g of TS-1 catalyst, prepared according to the above described procedure, were added, and heated to 70° C. by an oil bath. After the temperature of the mixture reached 70° C., 3.0 g of 31 weight % of hydrogen peroxide was added dropwise using a quantitative pump over 2 hours, and stirred further for 20 minutes after the addition. The reaction solution was analyzed by liquid chromatography, and the yields of hydroquinone and catechol were calculated. The results are shown in Table 1.

후처리

  1. customA stirrer, a cooler and a temperature indicator were provided to a four-necked flask
  2. additionwere added
  3. customreached 70° C.
  4. customover 2 hours
  5. additionafter the addition

출처 및 근거

ORD 기록
ord-d186916510c642398ce38322f1c0400d
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05426244

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