HCID 3432930, 화합물 → 2-(2-Chlorophenoxy)aniline

HRID 2210796노트

반응식

HRID 2210796 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N+:15]([O-])=O.[H][H]>O1CCCC1.[Ni]>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH2:15]

참가 물질

5

반응물 2

HCID 3432930HCID 3432930, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 125690122-(2-Chlorophenoxy)aniline

시약·촉매·용매 2

HCID 935Nickel촉매HCID 8028Tetrahydrofuran용매

실험 절차

A solution of 2-chloro-(2-nitrophenoxy)benzene (5.00 g) in tetrahydrofuran (100 mL) was shaken in a Parr Hydrogenator over Raney nickel at 5 psi hydrogen at room temperature for 4 hours. The catalyst was filtered from the reaction, and the solution was evaporated under vacuum to a yellowish oil which crystallized on standing. The solid was crushed, suspended in hexane and filtered to yield the title compound as a light orange solid. Mp: 44°-45° C.

후처리

  1. filtrationThe catalyst was filtered from the reaction
  2. customthe solution was evaporated under vacuum to a yellowish oil which
  3. customcrystallized
  4. customThe solid was crushed
  5. filtrationfiltered

출처 및 근거

ORD 기록
ord-6ffd3e060b3c4617a49ca880d5b13ca5
출처 데이터셋
uspto-grants-1995_10
특허 번호
US05461046

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