Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Methoxymethyl)-6-phenylthiothymine → 5-Methyl-6-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Methoxymethyl)-6-phenylthiothymine | HCID 54016372 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 5-Methyl-6-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one | HCID 18671027 | 28.1% |
반응 단계
To 100 ml of concentrated hydrochloric acid, 17.2 g (62 mmole) of 1-(methoxymethyl)-6-phenylthiothymine was added and allowed to react for 2 hours at 80° C. The reaction mixture was concentrated under reduced pressure and crystallized from ethanol to obtain 3.8 g of the target compound (Yield: 26%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05461060 |
| 출처 데이터셋 | uspto-grants-1995_10 |
| ORD ID | ord-0369532af2e4431695b46452e0db0fa1 |
| 출처 메모 | uspto-grants-1995_10 |