Benzoyl chloride → HCID 19378056, 화합물

HRID 2210995

반응식

HRID 2210995 반응식
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:10][C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[C:14]([S:21]([OH:24])(=[O:23])=[O:22])=[CH:13][C:12]=1[OH:25]>N1C=CC=CC=1.O>[OH:25][C:12]1[CH:13]=[C:14]([S:21]([O-:24])(=[O:22])=[O:23])[C:15]2[C:20]([C:11]=1[NH:10][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[CH:19][CH:18]=[CH:17][CH:16]=2.[NH+:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

참가 물질

5

반응물 2

HCID 7412Benzoyl chlorideHCID 83161-Amino-2-naphthol-4-sulfonic acid

생성물 1

HCID 19378056HCID 19378056, 화합물수율 60%

시약·촉매·용매 2

HCID 962Water용매HCID 1049Pyridine용매

실험 절차

Benzoyl chloride (1.8 ml) was added portionwise to a vigorously stirred suspension of 2.39 g 4-amino-3-hydroxy-1-napthalenesulfonic acid in a mixture of 50 ml pyridine and 20 ml water with cooling in an ice bath. The mixture was stirred for 2 hours at room temperature. The solid product was collected and washed with 10 ml of ice-cold water. Drying in a vacuum oven gave crude pyridinium 3-hydroxy-4-(N-benzoylamino)-1-naphthalenesulfonate (2.55 g, 60%); an analytical sample was prepared by recrystallization from a mixture of tetrahydrofuran and water (9:1), m.p. 225° C.

후처리

  1. temperaturewith cooling in an ice bath
  2. customThe solid product was collected
  3. washwashed with 10 ml of ice-cold water
  4. customDrying in a vacuum oven

출처 및 근거

ORD 기록
ord-4210e90399164713930232e9843d02d6
출처 데이터셋
uspto-grants-1995_10
특허 번호
US05461155

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