Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopentanepropanoic acid → N-5-Quinolinyl-cyclopentanepropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopentanepropanoic acid | HCID 8818 | — |
| 반응물 | 5-Aminoquinoline | HCID 11911 | — |
| 생성물 | N-5-Quinolinyl-cyclopentanepropanamide | HCID 2107517 | 24.1% |
반응 단계
Prepared according to the method of example 18, using 5-quinolinamine (250 mg) and cyclopentanepropanoic acid (270 mg). Purification (HPLC, Symmetry—0.1% aqueous trifluoroacetic acid/acetonitrile) followed by recrystallisation from methanol/ethyl acetate gave the title compound as a colourless solid (112 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07408065B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-a80433abb70a48ee91e47047b46d9861 |
| 출처 메모 | uspto-grants-2008_08 |