1-(Benzyl-methyl-amino)-heptan-3-one → 1-[Benzyl(methyl)amino]-3-hexanone

반응식

[CH2:1]([N:8]([CH3:17])[CH2:9][CH2:10][C:11](=[O:16])[CH2:12][CH2:13][CH2:14]C)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([Mg]Cl)CC>>[CH2:1]([N:8]([CH3:17])[CH2:9][CH2:10][C:11](=[O:16])[CH2:12][CH2:13][CH3:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 179819221-(Benzyl-methyl-amino)-heptan-3-one

HCID 178455855HCID 178455855, 화합물

생성물 1

HCID 4195861-[Benzyl(methyl)amino]-3-hexanone

실험 절차

Using a method similar to that for 1-(Benzyl-methyl-amino)-heptan-3-one, propylmagnesium chloride (2 M solution in diethyl ether) affords the title compound: mass spectrum (ion spray) m/z=220 (M+1): 1H NMR (CDCl3) δ 7.35-7.24 (m, 5H), 3.51 (s, 2H), 2.74-2.69 (m, 2H), 2.66-2.61 (m, 2H), 2.39 (t, 2H), 2.20 (s, 3H), 1.67-1.57 (m, 2H), 0.92(t, 3H).

출처 및 근거

ORD 기록: ord-5981ee199ffe46258ddf07838c48ee81
출처 데이터셋: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07417064B2

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