Formic Acid → 3-(3,4-Dimethoxyphenyl)propionic acid

HRID 2227019

반응식

HRID 2227019 반응식
FC1C=C[C:5]([CH:8]2[O:13]C(=O)CC(=O)[O:9]2)=CC=1.[CH:16](=O)[C:17]1[CH:26]=[CH:25][C:22]([O:23][CH3:24])=[C:19]([O:20][CH3:21])[CH:18]=1.C(O)=O>C(N(CC)CC)C>[CH3:21][O:20][C:19]1[CH:18]=[C:17]([CH2:16][CH2:5][C:8]([OH:13])=[O:9])[CH:26]=[CH:25][C:22]=1[O:23][CH3:24]

참가 물질

5

반응물 3

HCID 284Formic AcidHCID 8419VeratraldehydeHCID 199386822-(4-Fluorophenyl)-1,3-dioxane-4,6-dione

생성물 1

HCID 750193-(3,4-Dimethoxyphenyl)propionic acid

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

5.26 g (0.025 mol) of 2-(4-fluorophenyl)-1,3-dioxane-4,6-dione (m.p.: 166°-167° C.) and 4.15 g (0.025 mol) of veratraldehyde were added to 25 ml of the mixture of formic acid and triethylamine prepared as described in Example 1. The reaction was carried out according to Example 1.

후처리

  1. customprepared

출처 및 근거

ORD 기록
ord-93ad8b5c70aa4baeb0248dd498d8ee07
출처 데이터셋
uspto-grants-1994_09
특허 번호
US05350872

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