Propionyl chloride → HCID 20522459, 화합물

HRID 223116노트

반응식

HRID 223116 반응식
[Al+3].[Cl-].[Cl-].[Cl-].[CH:5]([CH:8]1[C:16]2[C:11](=[CH:12][C:13]([CH3:17])=[CH:14][CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH:9]1[CH3:20])([CH3:7])[CH3:6].[C:21](Cl)(=[O:24])[CH2:22][CH3:23]>[N+](C)([O-])=O>[C:21]([C:14]1[CH:15]=[C:16]2[C:11]([C:10]([CH3:19])([CH3:18])[CH:9]([CH3:20])[CH:8]2[CH:5]([CH3:7])[CH3:6])=[CH:12][C:13]=1[CH3:17])(=[O:24])[CH2:22][CH3:23]

참가 물질

5

반응물 3

HCID 62324Propionyl chlorideHCID 30178881,1,2,6-Tetramethyl-3-(propan-2-yl)-2,3-dihydro-1H-indeneHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 20522459HCID 20522459, 화합물수율 80%

시약·촉매·용매 1

HCID 6375Nitromethane용매

실험 절차

At 0°-5° C. a solution of 4 g AlCl3 in 50 ml nitromethane is added to a mixture of 6 g 1-isopropyl-2,3,3,5-tetramethyl indan (obtained according to example I or II) and 25 g propionyl chloride. Then the reaction mixture is stirred at room temperature during one hour and poured out into ice and extracted three times with ether. The solution in ether is washed neutral, dried and evaporated. The residue is distilled under diminished pressure to obtain 6-propionyl-1-isopropyl-2,3,3,5-tetramethyl indan in a yield of 80%. B.p. 145° C./1 mm Hg.

후처리

  1. additionpoured out into ice
  2. extractionextracted three times with ether
  3. washThe solution in ether is washed neutral
  4. customdried
  5. customevaporated
  6. distillationThe residue is distilled under diminished pressure

출처 및 근거

ORD 기록
ord-60b82b61028b4ae38084e967486dd022
출처 데이터셋
uspto-grants-1982_10
특허 번호
US04352748

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