Ethylenediamine → 2-Propanol, 1,1'-(1,2-ethanediyldiimino)bis-

HRID 2231168

반응식

HRID 2231168 반응식
[CH2:1]1[O:4][CH:2]1[CH3:3].[CH2:5]([NH2:8])[CH2:6][NH2:7]>C(O)C.CCOCC>[OH:4][CH:2]([CH3:3])[CH2:1][NH:7][CH2:6][CH2:5][NH:8][CH2:1][CH:2]([OH:4])[CH3:3]

참가 물질

5

반응물 2

HCID 3301EthylenediamineHCID 6378Propylene Oxide

생성물 1

HCID 1029642-Propanol, 1,1'-(1,2-ethanediyldiimino)bis-수율 28.5%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 3283Diethyl Ether용매

반응 조건

온도
20 °C

실험 절차

(IV-a): Propylene oxide (142.4 g, 2.4 mol) was added dropwise over a period of 11 hours to a solution of ethylenediamine (71.9 g, 1.2 mol) in 25 mL absolute ethanol and 10 mL of nitrogen purged distilled water at 90° C. After addition, the reaction was maintained for an additional hour, then cooled to room temperature (about 20° C.). The reaction solution was concentrated by rotary evaporation to give a milky white suspension which, upon dissolution in anhydrous ether, produced a white precipitate of N,N'-bis(2-hydroxypropyl)ethylenediamine in 28.5 percent yield. The product was crystallized from methanol/ethanol [m.p. 132° C., IR(Nujol):3250(OH); NMR(MeOHd4): δ3.8(m, 2H); 2.6(t, 8H); 1.2(d, 6H)].

후처리

  1. custompurged
  2. distillationdistilled water at 90° C
  3. additionAfter addition
  4. temperaturethe reaction was maintained for an additional hour
  5. concentrationThe reaction solution was concentrated by rotary evaporation
  6. customto give a milky white suspension which

출처 및 근거

ORD 기록
ord-8571396415344ba6ab015a0db0d1579d
출처 데이터셋
uspto-grants-1988_11
특허 번호
US04781921

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