m-Chloroperbenzoic acid → HCID 14329854, 화합물

HRID 2232264노트

반응식

HRID 2232264 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[CH2:11])[CH2:9][OH:10])=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:20])C=1>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([CH2:11][OH:20])[CH2:9][O:10]2)=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 106546892-(4-Chlorophenyl)prop-2-en-1-ol

생성물 1

HCID 14329854HCID 14329854, 화합물수율 72.2%

시약·촉매·용매 1

HCID 6212Chloroform용매3회

실험 절차

To a solution of the compound prepared in Example 4(c), β-(4-chlorophenyl)-β-methylene ethanol (1.05g) in chloroform (50 mL) add, with cooling, (ice bath) a solution of m-chloroperbenzoic acid (1.2g) in chloroform. Stir the chloroform solution for 4 hr. Wash the chloroform solution, successively, with aqueous 10% NaHSO3 (to remove excess per acid) followed by aqueous NaHCO3 and finally with water. Dry (Na2SO4) the chloroform solution. Remove the chloroform in vacuo to provide the title compound as a colourless oil (0.83 g). Use the title compound without any further purification in the next reaction.

후처리

  1. temperaturewith cooling
  2. washWash the chloroform solution
  3. dry with materialDry (Na2SO4) the chloroform solution
  4. customRemove the chloroform in vacuo

출처 및 근거

ORD 기록
ord-9ab5f7fdd1e04bbc9b95666df4faea19
출처 데이터셋
uspto-grants-1988_11
특허 번호
US04788190

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