Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 86742579, 화합물

HRID 2232827노트

반응식

HRID 2232827 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](/[C:9](/[CH2:13][CH2:14][CH2:15][CH3:16])=[CH:10]/[CH:11]=O)=[CH:5][CH:4]=1.[C:17]([CH:21]=P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([O:19][CH3:20])=[O:18]>C(Cl)(Cl)(Cl)Cl.ClCCl>[CH3:20][O:19][C:17](=[O:18])/[CH:21]=[CH:11]/[CH:10]=[C:9](/[C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)\[CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

5

반응물 2

HCID 17453Acetic acid, 2-(triphenylphosphoranylidene)-, methyl esterHCID 14547236HCID 14547236, 화합물

생성물 1

HCID 86742579HCID 86742579, 화합물

시약·촉매·용매 2

HCID 5943Carbon Tetrachloride용매HCID 6344Dichloromethane용매

실험 절차

As described in Example 99, (E)-3-(4-methoxyphenyl)-2-heptenal (10 g) was treated with (carbomethoxymethylene)triphenylphosphorane (17 g) in carbon tetrachloride (70 mL) and dichloromethane (15 mL) for 4 days at room temperature. The ester was isolated in the normal way and purified by HPLC (ether-hexane; 1:9) to furnish 8 g of (E,E)15-(4-methoxyphenyl)-2,4-nonadienoic acid methyl ester, as an oil.

출처 및 근거

ORD 기록
ord-6f9ccc25e33c424490fed1aae9c7197e
출처 데이터셋
uspto-grants-1988_11
특허 번호
US04788206

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