Hydrazine hydrate (1:1) → HCID 20146320, 화합물

반응식

[CH2:1]([C:3]1[N:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][C:18]([OH:20])=O)=[CH:11][CH:10]=2)[CH:5]=[C:6]([CH3:8])[N:7]=1)[CH3:2].O.[NH2:23][NH2:24]>>[CH2:1]([C:3]1[N:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH2:16][CH2:17][C:18](=[O:20])[NH:23][N:24]=3)=[CH:11][CH:10]=2)[CH:5]=[C:6]([CH3:8])[N:7]=1)[CH3:2]

참가 물질

반응물 2

HCID 24654Hydrazine hydrate (1:1)

HCID 20146350HCID 20146350, 화합물

생성물 1

HCID 20146320HCID 20146320, 화합물

실험 절차

Similarly, reaction of 4-(2-ethyl-4-methyl-1H-imidazol-1-yl)-γ-oxobenzenebutanoic acid with hydrazine hydrate according to the procedure of this Example gives 4,5-dihydro-6-[4-(2-ethyl-4-methyl-1H-imidazol-1-yl)-phenyl]-3(2H)-pyridazinone.

출처 및 근거

ORD 기록: ord-6e2d41026c8d4b458b21e599bc432471
출처 데이터셋: uspto-grants-1982_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04353905

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