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Loxoprofen → Calcium Stearate

HRID 2234142
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HRID 2234142 반응식
CC(C(O)=O)C1C=CC(CC2C(=O)CCC2)=CC=1.[OH-].[K+].[C:21]([OH:40])(=[O:39])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38].[OH-].[Ca+2:42].[OH-]>O>[C:21]([O-:40])(=[O:39])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38].[Ca+2:42].[C:21]([O-:40])(=[O:39])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 3965LoxoprofenHCID 5281Stearic Acid2회HCID 14797Potassium HydroxideHCID 6093208Calcium Hydroxide2회

생성물 1

HCID 15324Calcium Stearate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A lubricant composition was formed by first adding 40.00 gms of oxidized CS-600 low viscosity byproduct wax (viscosity: 11 cps; acid number: 14.7 mg KOH/gram; Mettler drop point: 109.5° C.), 29.46 gms of hydrocarbon wax and 98.30 gms of stearic acid to a reactor vessel. The combination was melted and held at 140° C. with slight agitation. Approximately 6.00 gms of calcium hydroxide was then added with agitation. The calcium hydroxide reacted with the stearic acid, forming a calcium stearate product and water as a byproduct. The high temperatures converted the water to steam, generating foam. Approximately 20.24 gms of glycerol monostearate was then added to dissipate the foam. Next, another 6.00 gms of calcium hydroxide was added to the vessel with agitation. The mixture was mixed until water formation stopped, and it was slowly stirred to remove any entrapped air. The mixture was then held for a finishing step such as prilling or pastiliating. The resulting lubricant composition contained 20.65% of an oxidized, low viscosity byproduct wax, 15.21% of a hydrocarbon wax, 6.91% residual stearic acid, 10.45% residual glycerol monostearate, and 46.77% calcium stearate. At 140° C., this lubricant composition had a viscosity of 300 centipoise and an acid number of 15.1 mg KOH/gram.

후처리

  1. customA lubricant composition was formed
  2. customheld at 140° C. with slight agitation

출처 및 근거

ORD 기록
ord-327031c214a74407ac239ba1f5bbd2a6
출처 데이터셋
uspto-grants-2010_05
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07709571B2

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