4,5-Dibromo-2-nitroaniline → 4,5-Dibromobenzene-1,2-diamine

HRID 223450노트

반응식

HRID 223450 반응식
[Br:1][C:2]1[CH:3]=[C:4]([C:6]([N+:10]([O-])=O)=[CH:7][C:8]=1[Br:9])[NH2:5].[H][H]>[Ni].C(O)C>[Br:1][C:2]1[C:8]([Br:9])=[CH:7][C:6]([NH2:10])=[C:4]([NH2:5])[CH:3]=1

참가 물질

5

반응물 2

HCID 127110274,5-Dibromo-2-nitroanilineHCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 121969444,5-Dibromobenzene-1,2-diamine

시약·촉매·용매 2

HCID 935Nickel촉매HCID 702Ethanol용매

실험 절차

Five grams of 3,4-dibromo-6-nitroaniline were suspended in 200 ml. of anhydrous ethanol to which was added about 10 g. of Raney nickel. The hydrogenation mixture was placed in a low pressure hydrogenation apparatus at a hydrogen pressure of 55 psi. A rapid uptake of hydrogen occurred which ceased after about 25 minutes, at which time the deep yellow color originally present had been discharged indicating complete reduction of the nitro group to an amino group. The hydrogenation was continued for another half hour and the hydrogenation mixture was then worked up by filtering off the catalyst, washing the filtered catalyst, and stripping the volatile constituents from the filtrate. A yield of 4.1 g. of 4,5-dibromo-o-phenylenediamine was obtained.

후처리

  1. waitThe hydrogenation was continued for another half hour
  2. filtrationby filtering off the catalyst
  3. washwashing the filtered catalyst

출처 및 근거

ORD 기록
ord-4a37a6c9df3a42889c4b7fcddb126bcc
출처 데이터셋
uspto-grants-1982_10
특허 번호
US04355030

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