1-[3-(tert-Butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea → 1-(3-Hydroxymethylphenyl)-3-mesitylthiourea
반응식
[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([NH:16][C:17]([NH:19][C:20]2[C:25]([CH3:26])=[CH:24][C:23]([CH3:27])=[CH:22][C:21]=2[CH3:28])=[S:18])[CH:13]=[CH:14][CH:15]=1)(C(C)(C)C)(C)C>C(O)C.Cl.O>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([NH:16][C:17]([NH:19][C:20]2[C:25]([CH3:26])=[CH:24][C:23]([CH3:27])=[CH:22][C:21]=2[CH3:28])=[S:18])[CH:13]=[CH:14][CH:15]=1참가 물질
5
실험 절차
To 0.56 g (0.1.4 mmol) of 1-[3-(tert-butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea in 10 mL of ethanol was added 10 drops of concentrated hydrochloric acid. After 30 min, the reaction was diluted with water and the precipitate that formed was collected to give 0.35 g (86%) of the title compound as a white powder.