2-(2,6-Dimethylmorpholin-4-yl)nicotinonitrile → [2-(2,6-Dimethylmorpholin-4-yl)pyridin-3-yl]methylamine

HRID 2240390노트

반응식

HRID 2240390 반응식
[CH3:1][CH:2]1[O:7][CH:6]([CH3:8])[CH2:5][N:4]([C:9]2[N:16]=[CH:15][CH:14]=[CH:13][C:10]=2[C:11]#[N:12])[CH2:3]1>[Ni]>[CH3:1][CH:2]1[O:7][CH:6]([CH3:8])[CH2:5][N:4]([C:9]2[C:10]([CH2:11][NH2:12])=[CH:13][CH:14]=[CH:15][N:16]=2)[CH2:3]1

참가 물질

3

반응물 1

HCID 685821892-(2,6-Dimethylmorpholin-4-yl)nicotinonitrile

생성물 1

HCID 16795690[2-(2,6-Dimethylmorpholin-4-yl)pyridin-3-yl]methylamine

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

The product of Example 134A and Raney/nickel were processed according to the method of Example 131C to provide the product. MS (ESI+) m/z 222 (M+H)+;

후처리

  1. customto provide the product

출처 및 근거

ORD 기록
ord-bb998f47483f4b44a02a0815d1213e7a
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07723367B2

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