Methyl bromoacetate → HCID 68583021, 화합물
반응식
[Br:1][C:2]1[CH:31]=[CH:30][C:5]([CH2:6][C:7]2[N:8]([CH2:20][C:21]3[CH:26]=[CH:25][C:24]([N+:27]([O-])=O)=[CH:23][CH:22]=3)[CH:9]=[C:10]([C:12]3[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=3[Cl:19])[N:11]=2)=[CH:4][CH:3]=1.Br[CH2:33][C:34]([O:36][CH3:37])=[O:35]>>[CH3:37][O:36][C:34](=[O:35])[CH2:33][NH:27][C:24]1[CH:25]=[CH:26][C:21]([CH2:20][N:8]2[CH:9]=[C:10]([C:12]3[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=3[Cl:19])[N:11]=[C:7]2[CH2:6][C:5]2[CH:30]=[CH:31][C:2]([Br:1])=[CH:3][CH:4]=2)=[CH:22][CH:23]=1참가 물질
3
실험 절차
2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-1-(4-nitro-benzyl)-1H-imidazole (2.6 g, 5 mmol) was reduced to amine and was reacted with methyl bromoacetate following general procedures D & E to give {4-[2-(4-bromo-benzyl)-4-(2,4-dichloro-phenyl)-imidazol-1-ylmethyl]-phenylamino}-acetic acid methyl ester.
출처 및 근거
- ORD 기록
- ord-6c4aa7e224504935aa8484699f3dc8dd
- 출처 데이터셋
- uspto-grants-2010_05
- 특허 번호
- US07723369B2