Iodine → HCID 178506332, 화합물

HRID 2243279

반응식

HRID 2243279 반응식
[F:1][C:2]([F:12])([C:7]1[CH:11]=[CH:10][NH:9][N:8]=1)[C:3]([F:6])([F:5])[F:4].[N+]([O-])([O-])=O.[NH4+].[Ce].[Ce].[I:20]I>C(#N)C>[I:20][C:11]1[C:7]([C:2]([F:1])([F:12])[C:3]([F:6])([F:5])[F:4])=[N:8][NH:9][CH:10]=1

참가 물질

5

반응물 3

HCID 807IodineHCID 86617141Dicerium ammonium nitrateHCID 1785063263-(pentafluoroethyl)-1H-pyrazole

생성물 1

HCID 178506332HCID 178506332, 화합물수율 162.7%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

An acetonitrile solution (20 ml) of 3-pentafluoroethyl-1H-pyrazole (2.0 g), dicerium ammonium nitrate (3.0 g) and iodine (1.6 g) was refluxed for 3 hours. After cooling, the reaction solution was washed with saturated aqueous solution of sodium thiosulfate and saturated aqueous solution of sodium chloride. After drying the organic layer with magnesium sulfate, the solvent was distilled off under the reduced pressure to obtain 4-iodo-3-pentafluoroethyl-1H-pyrazole (3.2 g).

후처리

  1. temperatureAfter cooling
  2. washthe reaction solution was washed with saturated aqueous solution of sodium thiosulfate and saturated aqueous solution of sodium chloride
  3. dry with materialAfter drying the organic layer with magnesium sulfate
  4. distillationthe solvent was distilled off under the reduced pressure

출처 및 근거

ORD 기록
ord-616beeebfdde422abc9d876986fc83e7
출처 데이터셋
uspto-grants-2010_03
특허 번호
US07674807B2

연결된 노트

불러오는 중…