Cyclopentanol → (6-Cyclopentyloxy-quinazolin-4-yl)-thiazolo[5,4-b]-pyridin-2-yl-amine
반응식
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH:13]1(O)[CH2:17][CH2:16][CH2:15][CH2:14]1.[N:19]1[C:27]2[C:22](=[N:23][CH:24]=[CH:25][CH:26]=2)[S:21][C:20]=1[NH2:28]>>[CH:13]1([O:12][C:9]2[CH:10]=[C:11]3[C:6](=[CH:7][CH:8]=2)[N:5]=[CH:4][N:3]=[C:2]3[NH:28][C:20]2[S:21][C:22]3[C:27]([N:19]=2)=[CH:26][CH:25]=[CH:24][N:23]=3)[CH2:17][CH2:16][CH2:15][CH2:14]1참가 물질
4
실험 절차
The compound of Example 26 was manufactured by the same method as in Example 22, by a similar method thereto or by a combination of such a method with a conventional method using 4-chloro-6-hydroxy-quinazoline, cyclopentanol and thiazolo[5,4-b]pyridin-2-yl-amine.
출처 및 근거
- ORD 기록
- ord-300dad7b748547388954b41f83e39d90
- 출처 데이터셋
- uspto-grants-2010_03