Sodium borohydride → Tricyclohexylstannane

HRID 2246796

반응식

HRID 2246796 반응식
C(OCC)C.O.[BH4-].[Na+].[OH-].[CH:10]1([Sn+:16]([CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)[CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1>C(OCC)C>[CH:23]1([SnH:16]([CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1

참가 물질

5

반응물 3

HCID 4311764Sodium borohydrideHCID 9864905CyhexatinHCID 21584184Diethylether water

생성물 1

HCID 25729Tricyclohexylstannane

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A mixture (400 mL) of diethyl oxide:water 1:1 was cooled at 0° C. under nitrogen in a three-necked flask of 1 L. Sodium borohydride (3 g, 79.4 mmol) and then tricyclohexyltin hydroxide (30 g, 62.2 mmol) were successively and carefully added. After addition of 100 mL of diethyl oxide, the mixture was stirred 2 days at room temperature. After separation, the organic layer was dried over magnesium sulphate and evaporated under reduced pressure. The crude product was distilled under high vacuum to afford, a colourless oil (23.23 g; 63 mmol).

후처리

  1. additioncarefully added
  2. customAfter separation
  3. dry with materialthe organic layer was dried over magnesium sulphate
  4. customevaporated under reduced pressure
  5. distillationThe crude product was distilled under high vacuum
  6. customto afford

출처 및 근거

ORD 기록
ord-b44fc5b2e02b4f41b2340ea7ba6f0749
출처 데이터셋
uspto-grants-2010_03
특허 번호
US07687581B2

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