Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chlorobenzenesulfonamide → 4-[5-[2-(N',N'-Dimethylureido)propyl]-1-methylindol-3-ylmethyl]-3-methoxy-N-(2-chlorophenylsulfonyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chlorobenzenesulfonamide | HCID 81410 | — |
| 반응물 | 4-[5-[2-(N',N'-dimethylureido)propyl]-1-methylindol-3-ylmethyl]-3-methoxybenzoic acid | HCID 57195283 | — |
| 생성물 | 4-[5-[2-(N',N'-Dimethylureido)propyl]-1-methylindol-3-ylmethyl]-3-methoxy-N-(2-chlorophenylsulfonyl)benzamide | HCID 57020800 | — |
반응 단계
Using a similar procedure to that described in Example 2, part c, except starting from 4-[5-[2-(N',N'-dimethylureido)propyl]-1-methylindol-3-ylmethyl]- 3-methoxybenzoic acid, and using 2-chlorophenylsulfonamide instead of 2-methylphenylsulfonamide, the title compound was obtained (88%) as a white solid; mp 131°-136° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05041460 |
| 출처 데이터셋 | uspto-grants-1991_08 |
| ORD ID | ord-b7475bf950634a30a2c723532b5a469b |
| 출처 메모 | uspto-grants-1991_08 |