Hydrogen Bromide → 5-Chloro-2,3-dihydroxybenzoic acid

HRID 2251592

반응식

HRID 2251592 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([O:12]C)[C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].Br>C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[C:4]([OH:12])[C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

참가 물질

4

반응물 2

HCID 260Hydrogen BromideHCID 6765015-Chloro-2-hydroxy-3-methoxybenzoic acid

생성물 1

HCID 123948825-Chloro-2,3-dihydroxybenzoic acid

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

step a) 2-hydroxy-3-methoxy-benzoic acid (13) is chlorinated for example with N-chlorosuccinimide in acetic acid to yield 5-chloro-2-hydroxy-3-methoxy benzoic acid (14); step b) the methoxy group of compound (14) is reacted with hydrobromic acid in acetic acid to yield 5-chloro-2,3-dihydroxybenzoic acid (15);

출처 및 근거

ORD 기록
ord-9a29f7d755374984b439cf51bfb41774
출처 데이터셋
uspto-grants-2008_01
특허 번호
US07319101B2

연결된 노트

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