반응식
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:4]=[C:5]([C:9](=[O:11])[CH3:10])[CH:6]=[CH:7][CH:8]=1.CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>>[CH3:16][N:17]([CH3:19])[CH:18]=[CH:10][C:9]([C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:12])([F:13])[F:1])[CH:4]=1)=[O:11]참가 물질
3
실험 절차
A reaction mixture of 50 g. of m-trifluoromethylacetophenone and 50 ml. of dimethylformamide dimethylacetal is refluxed for 16 hours under anhydrous conditions and then evaporated in vacuo to a thick orange-red oil. Hexane is added, the mixture is chilled and the desired product is collected by filtration as yellow crystals, m.p. 60.5°-62° C.
후처리
- additionA reaction mixture of 50 g
- customevaporated in vacuo to a thick orange-red oil
- additionHexane is added
- temperaturethe mixture is chilled
- filtrationthe desired product is collected by filtration as yellow crystals, m.p. 60.5°-62° C.
출처 및 근거
- ORD 기록
- ord-563b351be4444408818fafacaa17972b
- 출처 데이터셋
- uspto-grants-1980_11
- 특허 번호
- US04236005
연결된 노트
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