Thionyl Chloride → Methyl 3-(chlorocarbonyl)-5-nitrobenzoate

HRID 2253593

반응식

HRID 2253593 반응식
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([N+:14]([O-:16])=[O:15])[CH:13]=1)[C:8](O)=[O:9])=[O:4].O=S(Cl)[Cl:19]>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([N+:14]([O-:16])=[O:15])[CH:13]=1)[C:8]([Cl:19])=[O:9])=[O:4]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 747761,3-Benzenedicarboxylic acid, 5-nitro-, 1-methyl ester

생성물 1

HCID 74774Methyl 3-(chlorocarbonyl)-5-nitrobenzoate

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Heat 3-methoxycarbonyl-5-nitrobenzoic acid (2.0 g=8.9 mmol) with SOCl2 (2.1 g=18 mmol) in toluene at reflux 1 hr. Concentrate to obtain 3-methoxycarbonyl-5-nitrobenzoyl chloride, m.p. 66°-8° C.

후처리

  1. temperatureat reflux 1 hr
  2. concentrationConcentrate

출처 및 근거

ORD 기록
ord-58d1af3e19f64ebeaafb93c0ff9d8920
출처 데이터셋
uspto-grants-1993_08
특허 번호
US05232920

연결된 노트

불러오는 중…