Hydrochloric Acid → HCID 19739392, 화합물

HRID 2254986노트

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HRID 2254986 반응식
C1CO[CH:3]([CH2:4][CH2:5][CH2:6][C:7]2[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=2)[O:2]1.O1CCCC1.Cl>O>[C:11]([C:10]1[CH:13]=[CH:14][C:7]([CH2:6][CH2:5][CH2:4][CH:3]=[O:2])=[CH:8][CH:9]=1)#[N:12]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 10856924HCID 10856924, 화합물

생성물 1

HCID 19739392HCID 19739392, 화합물수율 116.5%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 2.8 g of p-(4,4-ethylenedioxybutyl)benzonitrile, 56 ml of tetrahydrofuran and 56 ml of 10 percent hydrochloric acid was stirred for 3 hours at room temperature and then left to stand overnight. Thereafter, the reaction mixture was diluted with water and extracted three times with diethyl ether. The organic phases were washed twice with water, dried over magnesium sulphate, filtered and concentrated. There were obtained 2.6 g of 4-(p-cyanophenyl)butyraldehyde which was processed without additional purification.

후처리

  1. waitleft
  2. waitto stand overnight
  3. extractionextracted three times with diethyl ether
  4. washThe organic phases were washed twice with water
  5. dry with materialdried over magnesium sulphate
  6. filtrationfiltered
  7. concentrationconcentrated

출처 및 근거

ORD 기록
ord-d73b6f1f23034d24af0304684cfb5ff2
출처 데이터셋
uspto-grants-1993_08
특허 번호
US05238602

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