Hydrochloric Acid → 5-Thiazol-2-yl-2,3-dihydro-1H-isoindole
반응식
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([C:17]3[S:18][CH:19]=[CH:20][N:21]=3)[CH:14]=2)[CH2:9]1)=O)(C)(C)C.Cl>>[S:18]1[CH:19]=[CH:20][N:21]=[C:17]1[C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][CH:12]=1)[CH2:9][NH:8][CH2:16]2참가 물질
3
실험 절차
Prepared in analogy to Example A3(e) from 5-Thiazol-2-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and using trifluoacetic acid instead of hydrochloride acid. Yellow gum. MS (m/e): 202.8 ([M+H]+, 100%)
출처 및 근거
- ORD 기록
- ord-41c7f31e143f40d08171111c0b1aa56e
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07557114B2
반응 노트
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