Hydrochloric Acid → 5-Methyl-6-morpholin-4-yl-2,3-dihydro-1H-isoindole hydrochloride
반응식
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][C:12]([N:18]3[CH2:23][CH2:22][O:21][CH2:20][CH2:19]3)=[C:13]([CH3:17])[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:24]>>[ClH:24].[CH3:17][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][C:12]=1[N:18]1[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1)[CH2:9][NH:8][CH2:16]2참가 물질
3
실험 절차
Prepared in analogy to Example A3(e) from 5-methyl-6-morpholin-4-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown solid. MS (m/e): 219.3 ([M+H]+, 100%).
출처 및 근거
- ORD 기록
- ord-bc1313b18a66428083130e92c47740f2
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07557114B2
반응 노트
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