4-(3-Isopropyl-4-methoxy-phenoxy)-3,5-dimethyl-nitrobenzene → 3,5-Dimethyl4-(3'-isopropyl-4'-methoxyphenoxy)-aniline

HRID 2256480노트

반응식

HRID 2256480 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([N+:21]([O-])=O)[CH:5]=[C:6]([CH3:20])[C:7]=1[O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([CH:17]([CH3:19])[CH3:18])[CH:10]=1>[Pt].C(O)C>[CH3:20][C:6]1[CH:5]=[C:4]([CH:3]=[C:2]([CH3:1])[C:7]=1[O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([CH:17]([CH3:18])[CH3:19])[CH:10]=1)[NH2:21]

참가 물질

4

반응물 1

HCID 103136024-(3-Isopropyl-4-methoxy-phenoxy)-3,5-dimethyl-nitrobenzene

생성물 1

HCID 100167993,5-Dimethyl4-(3'-isopropyl-4'-methoxyphenoxy)-aniline

시약·촉매·용매 2

HCID 23939Platinum촉매HCID 702Ethanol용매

실험 절차

3,5-Dimethyl-4-(3'-isopropyl-4'-methoxyphenoxy)-nitrobenzene (6.0 g) and 600 mg of 10% platinum on carbon in 200 ml ethanol are hydrogenated on a Parr shaker. Catalyst is removed by filtration through Celite and the filtrate is stripped to afford 3,5dimethyl-4-(3'-isopropyl-4'-methoxyphenoxy)-aniline.

후처리

  1. customCatalyst is removed by filtration through Celite

출처 및 근거

ORD 기록
ord-72da1e0d97e24611bff6b7e94c53b434
출처 데이터셋
uspto-grants-1997_08
특허 번호
US05654468

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