Methyl iodide → 2-Methoxy-4-methylpyridin-3-amine

HRID 2257171노트

반응식

HRID 2257171 반응식
[N+:1]([C:4]1[C:5](=[O:11])[NH:6][CH:7]=[CH:8][C:9]=1[CH3:10])([O-])=O.[CH3:12]I>[Zn].C(O)(=O)C>[CH3:12][O:11][C:5]1[C:4]([NH2:1])=[C:9]([CH3:10])[CH:8]=[CH:7][N:6]=1

참가 물질

5

반응물 2

HCID 6328Methyl iodideHCID 3453702-Hydroxy-4-methyl-3-nitropyridine

생성물 1

HCID 103293612-Methoxy-4-methylpyridin-3-amine

시약·촉매·용매 2

HCID 23994Zinc촉매HCID 176Acetic Acid용매

실험 절차

3-Nitro-4-methyl-2-pyridone was methylated with methyl iodide and reduced with zinc and acetic acid to give 2-methoxy-3-amino-4-methylpyridine. This material was converted to the title compound according to the procedure described in Example 28.

출처 및 근거

ORD 기록
ord-1621b4acbbdb498e96ed951c5e9ba050
출처 데이터셋
uspto-grants-1997_08
특허 번호
US05656634

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