1H-Indazole-5,6-diamine → 6-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline 7-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline

HRID 2260110

반응식

HRID 2260110 반응식
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[NH2:11])[NH:7][N:6]=[CH:5]2.[Cl:12][C:13]1[S:14][C:15]([C:18](=O)[CH:19]=O)=[CH:16][CH:17]=1>C(O)C>[Cl:12][C:13]1[S:14][C:15]([C:18]2[CH:19]=[N:1][C:2]3[CH:3]=[C:4]4[CH:5]=[N:6][NH:7][C:8]4=[CH:9][C:10]=3[N:11]=2)=[CH:16][CH:17]=1.[Cl:12][C:13]1[S:14][C:15]([C:18]2[CH:19]=[N:11][C:10]3[CH:9]=[C:8]4[NH:7][N:6]=[CH:5][C:4]4=[CH:3][C:2]=3[N:1]=2)=[CH:16][CH:17]=1

참가 물질

4

반응물 2

HCID 819001H-Indazole-5,6-diamineHCID 187887102-Chloro-5-glyoxyloylthiophene

생성물 1

HCID 189998206-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline 7-(5-chlorothien-2-yl)-1H-pyrazolo[3,4-g]quinoxaline

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

To a mixture of 5,6-diaminoindazole (0.5 g) in 30 ml absolute ethanol is added slowly a solution of 2-chloro-5-glyoxyloylthiophene (0.72 g) and 20 ml ethanol. The resulting mixture is stirred at room temperature for 4.5 hours. The yellow solid which forms is filtered off, washed with ethanol then with hexane and air dried overnight.

후처리

  1. filtrationThe yellow solid which forms is filtered off
  2. washwashed with ethanol
  3. dry with materialwith hexane and air dried overnight

출처 및 근거

ORD 기록
ord-5922bbc9349b42c8bc5ca660f6846243
출처 데이터셋
uspto-grants-1995_12
특허 번호
US05476851

연결된 노트

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