Thionyl Chloride → 3,7,11,15-Tetramethylhexadecanoyl chloride

HRID 2260953

반응식

HRID 2260953 반응식
[C:1]([OH:22])(=O)[CH2:2][CH:3]([CH2:5][CH2:6][CH2:7][CH:8]([CH2:10][CH2:11][CH2:12][CH:13]([CH2:15][CH2:16][CH2:17][CH:18]([CH3:20])[CH3:19])[CH3:14])[CH3:9])[CH3:4].S(Cl)([Cl:25])=O>N1C=CC=CC=1.C(Cl)Cl>[C:1]([Cl:25])(=[O:22])[CH2:2][CH:3]([CH2:5][CH2:6][CH2:7][CH:8]([CH2:10][CH2:11][CH2:12][CH:13]([CH2:15][CH2:16][CH2:17][CH:18]([CH3:20])[CH3:19])[CH3:14])[CH3:9])[CH3:4]

참가 물질

5

반응물 2

HCID 24386Thionyl ChlorideHCID 26840Phytanic Acid

생성물 1

HCID 148021433,7,11,15-Tetramethylhexadecanoyl chloride수율 98.2%

시약·촉매·용매 2

HCID 1049Pyridine촉매HCID 6344Dichloromethane용매

실험 절차

Under a nitrogen atmosphere, one drop of pyridine was added to 2.5 g of phytanic acid and 12.5 ml of methylene chloride, and 1.43 g of thionyl chloride was added dropwise thereto at room temperature. After the completion of dropwise addition, the resultant was refluxed for 1 hour, and concentrated under reduced pressure to obtain about 2.6 g of phytanic acid chloride.

후처리

  1. additionwas added dropwise
  2. customat room temperature
  3. additionAfter the completion of dropwise addition
  4. temperaturethe resultant was refluxed for 1 hour
  5. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-856cd64f0a5f413198dbd4061f6bead4
출처 데이터셋
uspto-grants-2010_12
특허 번호
US07846903B2

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