Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2,4-Dihydroxy-3-methylphenyl)ethan-1-one → 2-(3-((4-Acetyl-3-hydroxy-2-methylphenoxy)methyl)phenylthio) isonicotinonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2,4-Dihydroxy-3-methylphenyl)ethan-1-one | HCID 592139 | — |
| 반응물 | 2-{[3-(Hydroxymethyl)phenyl]sulfanyl}pyridine-4-carbonitrile | HCID 57355460 | — |
| 생성물 | 2-(3-((4-Acetyl-3-hydroxy-2-methylphenoxy)methyl)phenylthio) isonicotinonitrile | HCID 68537769 | 52% |
반응 단계
Using the method of Preparation 166 using 2-(3-(hydroxymethyl)phenylthio) isonicotinonitrile (1.46 g, 6.02 mmol) and 1-(2,4-dihydroxy-3-methylphenyl)ethanone (1.00 g, 6.02 mmol) affords the title compound (1.22 g, 52%). MS (APCI-neg) m/z (rel intensity): 389 (M−H, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07858646B2 |
| 출처 데이터셋 | uspto-grants-2010_12 |
| ORD ID | ord-ebc5f64e2797474d8bf03e3017a24606 |
| 출처 메모 | uspto-grants-2010_12 |