HCID 59600214, 화합물 → HCID 66841605, 화합물
반응식
[CH2:1]([O:3][C:4]([C:6]1[CH2:7][CH2:8][N:9]2[C:14](=[O:15])[CH2:13][O:12][CH2:11][C:10]=12)=[O:5])[CH3:2]>C(O)(=O)C.C(Cl)Cl.[Pt](=O)=O>[CH2:1]([O:3][C:4]([CH:6]1[CH:10]2[CH2:11][O:12][CH2:13][C:14](=[O:15])[N:9]2[CH2:8][CH2:7]1)=[O:5])[CH3:2]참가 물질
5
실험 절차
A solution of 68 (1.056 g, 5.0 mmol) in 25 ml of acetic acid is hydrogenated over 1.056 g of platinum dioxide at RT and normal pressure for 18 hours. The black suspension is diluted with 20 ml of DCM and filtered through a pad of celite. The filtrate is evaporated to give 1.09 g of a yellow oil which is purified by chromatography (Silica gel 60, 0.063-0.2 mesh, ethyl acetate/ethanol 9:1).
후처리
- filtrationfiltered through a pad of celite
- customThe filtrate is evaporated
출처 및 근거
- ORD 기록
- ord-3222f042cf344482901acd414fbceddd
- 출처 데이터셋
- uspto-grants-2010_12
- 특허 번호
- US07858781B2
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