Methyl iodide → Methyl 2-methoxy-4-nitrobenzoate

HRID 226804

반응식

HRID 226804 반응식
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].[C:15](=O)([O-])[O-].[K+].[K+].IC>>[CH3:1][O:2][C:3]1[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5]([O:7][CH3:15])=[O:6]

참가 물질

4

반응물 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 757764-Nitro-o-anisic acid

생성물 1

HCID 10798535Methyl 2-methoxy-4-nitrobenzoate수율 77.7%

실험 절차

In a manner analogous to the preparation of N2,N4-bis[4-(2-methyl-1,2,3,4-tetrazol-5-yl)methyleneoxyphenyl]-5-fluoro-2,4-pyrimidinediamine, 2-methoxy-4-nitrobenzoic acid (1 g, 5 mmol), potassium carbonate (1.4 g, 10 mmol) and iodomethane (0.47 mL, 7.5 mmol) gave methyl 2-methoxy-4-nitrobenzoate (820 mg, 77%) as a white solid.

출처 및 근거

ORD 기록
ord-a29423181043408ab818a63b480d4007
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557210B2

연결된 노트

불러오는 중…