Ammonia → HCID 178508977, 화합물
반응식
[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][OH:15])[N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([O:23]C)[N:6]2[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.N>Cl>[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][OH:15])[N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([OH:23])[N:6]2[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1참가 물질
4
실험 절차
6-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurine (83 mg, 0.25 mmol) in concentrated hydrochloric acid (5 ml) was stirred at room temperature for 4 hours. The reaction mixture was neutralized with 28% aqueous ammonia and the resulting crystals were filtered and washed with water to give the subject compound (40 mg, yield 51%).
후처리
- filtrationthe resulting crystals were filtered
- washwashed with water
출처 및 근거
- ORD 기록
- ord-c3f16079a0c445ff8e00430a4c89f364
- 출처 데이터셋
- uspto-grants-2001_12
- 특허 번호
- US06329381B1
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