Sodium borohydride → HCID 70189115, 화합물

HRID 2269498노트

반응식

HRID 2269498 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([N+:26]([O-])=O)[CH:21]=2)[NH:10][C:11]([CH3:19])([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH3:12])=[CH:5][CH:4]=1.[BH4-].[Na+]>O.O.O.O.O.O.[Ni](Cl)Cl.CO>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]([NH:10][C:11]([CH3:19])([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH3:12])[C:20]2[CH:21]=[C:22]([NH2:26])[CH:23]=[CH:24][CH:25]=2)=[CH:7][CH:8]=1

참가 물질

5

반응물 2

HCID 4311764Sodium borohydrideHCID 18334081HCID 18334081, 화합물

생성물 1

HCID 70189115HCID 70189115, 화합물수율 94.6%

시약·촉매·용매 2

HCID 11791229Dichloronickel;hexahydrate촉매HCID 887Methanol용매

실험 절차

Following a similar procedure to that described in Example (94b), 1.39 g of N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]-N-(1-methyl-1-phenylethyl)amine [prepared as described in step (a) above], 1.76 g of nickel chloride hexahydrate, 559 mg of sodium borohydride and 100 ml of methanol were reacted, to obtain 1.21 g of the title compound as a yellow oil.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-758f9eb6510b4fc5866ea9103a1ee204
출처 데이터셋
uspto-grants-2001_12
특허 번호
US06329405B1

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