Phenol, 4-methoxy-2-nitro- → 2-Amino-4-methoxyphenol
반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[C:5]([N+:10]([O-])=O)[CH:4]=1>CO.[Pd]>[NH2:10][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[CH:7][C:6]=1[OH:9]참가 물질
4
실험 절차
Commercially available 4-methoxy-2-nitrophenol (1 g, 5.9 mmol), a compound of formula (C) was dissolved in 10 mL of methanol, and then 10% Pd/C was added to the mixture. The mixture was hydrogenated in a Parr™ shaker at 30 psi until consumption of hydrogen stopped. The mixture was filtered through Celite and concentrated, to yield 2-amino-4-methoxyphenol a compound of formula (d), which was used without further purification.
후처리
- customThe mixture was hydrogenated in a Parr™ shaker at 30 psi until consumption of hydrogen
- filtrationThe mixture was filtered through Celite
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-357d0f6dda4445b290f863c893983868
- 출처 데이터셋
- uspto-grants-2005_02
- 특허 번호
- US06849632B2
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